4-硫代尿苷,英文名:4-Thiouridine,CAS:13957-31-8,4-Thiouridine is a photoreactive (crosslinking) uridine anal

2026-03-27 10:24:45

13957-31-8

4-硫代尿苷(4-Thiouridine)

CAS: 13957-31-8

化学式: C9H12N2O5S

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中文名 4-硫代尿苷
英文名 4-Thiouridine
别名 4-巯基尿苷
4-硫代尿苷
1-((2R,3R,4S,5R)-3,4-二羟基-5-(羟甲基)四氢呋喃-2-基)-4-硫代-3,4-二氢嘧啶-2(1H)-酮
英文别名 NSC 518132
Thiouridine
thiouridine
4-THIOURIDINE
4-Thiouridine
THIOURIDINE, 4-
1-((2R,3R,4S,5R)
4-Thio-D-uridine
Uridine, 4-thio-
Thiouridine (VAN)
4-thiouridineapprox.
-4-thioxo-3,4-dihydropyrimidin-2(1H)
1-pentofuranosyl-4-thioxo-3,4-dihydropyrimidin-2(1H)-one
1-beta-D-ribofuranosyl-4-thioxo-3,4-dihydropyrimidin-2(1H)-one
1-((2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxyMethyl)tetrahydrofuran-2-yl)-4-thioxo-3,4-dihydropyriMidin-2(1H)-one
CAS 13957-31-8
EINECS 237-735-3
化学式 C9H12N2O5S
分子量 260.27
InChI InChI=1/C9H12N2O5S/c12-3-4-6(13)7(14)8(16-4)11-2-1-5(17)10-9(11)15/h1-2,4,6-8,12-14H,3H2,(H,10,15,17)
InChIKey ZLOIGESWDJYCTF-XVFCMESISA-N
密度 1.72±0.1 g/cm3(Predicted)
熔点 139-140℃ (ethanol )
水溶性 Soluble in water (20 mg/ml), and methanol (10 mg/ml).
溶解度 DMSO (微溶),甲醇 (微溶,超声处理)
折射率 1.732
酸度系数 4.75±0.20(Predicted)
存储条件 -20°C
外观 结晶
颜色 light yellow
产品用途 4-Thiouridine is a photoreactive (crossling) uridine analogue that upon phosphorylation to 4-thioUTP may be incorporated into RNA structures. 4-Thiouridine may be used to study the specificity and kinetics of uridine-cytidine kinases.
MDL号 MFCD00006538
安全术语 24/25 - 避免与皮肤和眼睛接触。
WGK Germany 3
海关编号 29349990

13957-31-8 - 介绍

4-Thiouridine is a thionucleobase used as an antisense agent.最后更新:2022-10-16 17:13:49
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