伊伐布雷定,英文名:Ivabradine,CAS:155974-00-8,化学式:C27H36N2O5,分子量:468.59,密度:1.146±0.06 g/cm3(Predicted),沸点:626

155974-00-8 询问

伊伐布雷定(Ivabradine)

CAS: 155974-00-8

化学式: C27H36N2O5

var head = document.getElementsByTagName('HEAD').item(0); var script = document.createElement('SCRIPT'); script.src = "https://www.chembk.com/assets/js/qrcode.min.js"; script.type = "text/javascript"; head.appendChild(script); } () { var url = window.location.href; var qrcode = new QRCode(document.getElementById("qrcode"), { width: 200, height: 200, useSVG: true qrcode.makeCode(url); }

中文名	伊伐布雷定
英文名	Ivabradine
别名	伐布雷定 依法布雷定 依伐布雷定 伊伐布雷定 伊伐布雷定-D3
英文别名	S 16257 S-16257-2 S 16257-2 Ivabradine Ivabridine – UNII-3H48L0LPZQ Ivabradine sulfate Ivabradine(Hydrochloride form) 7,8-Dimethoxy-3-(3-(((4,5-dimethoxybenzocyclobutan-1-yl)methyl)methylamino)propyl)-1,3,4,5-tetrahydro-2H-benzazepin-2-one 3-[3-[[(8S)-3,4-dimethoxy-8-bicyclo[4.2.0]octa-1,3,5-trienyl]methyl-methylamino]propyl]-7,8-dimethoxy-2,5-dihydro-1H-3-benzazepin-4-one 3-[3-[[(8S)-3,4-dimethoxy-8-bicyclo[4.2.0]octa-1,3,5-trienyl]methyl-methyl-amino]propyl]-7,8-dimethoxy-2,5-dihydro-1H-3-benzazepin-4-one 7-(3-((((R)-4,5-diMethoxy-1,2-dihydrocyclobutabenzen-1-yl)Methyl)(Methyl)aMino)propyl)-2,3-diMethoxy-8,9-dihydro-5H-benzo[7]annulen-6(7H)-one (S)-3-(3-(((3,4-Dimethoxybicyclo(4.2.0)octa-1,3,5-trien-7-yl)methyl)methylamino)propyl)-1,3,4,5-tetrahydro-7,8-dimethoxy-2H-3-benzazepin-2-one 3-(3-((((7S)-3,4-Dimethoxybicyclo(4.2.0)octa-1,3,5-trien-7-yl)methyl)methylamino)propyl)-1,3,4,5-tetrahydro-7,8-dimethoxy-2H-3-benzazepin-2-one 2H-3-Benzazepin-2-one, 3-[3-[[[(7S)-3,4-dimethoxybicyclo[4.2.0]octa-1,3,5-trien-7-yl]methyl]methylamino]propyl]-1,3,4,5-tetrahydro-7,8-dimethoxy- 3-{3-[{[(7S)-3,4-dimethoxybicyclo[4.2.0]octa-1,3,5-trien-7-yl]methyl}(methyl)amino]propyl}-7,8-dimethoxy-1,3,4,5-tetrahydro-2H-3-benzazepin-2-one 2H-3-Benzazepin-2-one, 3-(3-(((3,4-dimethoxybicyclo(4.2.0)octa-1,3,5-trien-7-yl)methyl)methylamino)propyl)-1,3,4,5-tetrahydro-7,8-dimethoxy-, (S)-
CAS	155974-00-8
化学式	C27H36N2O5
分子量	468.59
InChI	InChI=1/C27H36N2O5/c1-28(17-21-11-20-14-25(33-4)26(34-5)16-22(20)21)8-6-9-29-10-7-18-12-23(31-2)24(32-3)13-19(18)15-27(29)30/h12-14,16,21H,6-11,15,17H2,1-5H3/t21-/m1/s1
密度	1.146±0.06 g/cm3(Predicted)
沸点	626.9±55.0 °C(Predicted)
闪点	332.9°C
蒸汽压	1.24E-15mmHg at 25°C
折射率	1.56
酸度系数	8.77±0.50(Predicted)
存储条件	-20°C
物化性质	伊伐布雷定的盐酸盐为橙色薄膜衣片，5mg片剂为椭圆形，7.5mg片剂为三角形，除去包衣显白色。可用于对β受体阻滞药有禁忌或不能耐受的正常窦性节律的慢性稳定型心绞痛的对症治疗，它通过选择性抑制负责控制窦房结自动去极化和调节心率的If通道发挥作用，Procoralan 选择性作用于窦房结，对心内传导、心肌收缩或心室复极化没有影响。