Quinidine Hydrochloride,英文名:Quinidine Hydrochloride,CAS:6151-40-2,化学式:C20H24N2O2.ClH.H2O,分子量:378.9,熔

6151-40-2 询问

Quinidine Hydrochloride(Quinidine Hydrochloride)

CAS: 6151-40-2

化学式: C20H24N2O2.ClH.H2O

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中文名	Quinidine Hydrochloride
英文名	Quinidine Hydrochloride
别名	奎尼丁盐酸盐 奎寧定鹽酸鹽 奎尼丁单盐酸盐一水合物 奎尼丁 盐酸盐 一水合物
英文别名	Quinidine Hydrochloride QUINIDINE HYDROCHLORIDE QUINIDINE HYDROCHLORIDE MONOHYDRATE Quinidine monohydrate hydrochloride Quinidine monohydrochloride monohydrate QUINIDINE HYDROCHLORIDE MONOHYDRATE CRYSTALLINE 6μ-Methoxycinchonan-9-ol hydrochloride monohydrate Quinidine hydrochloride monohydrate technical grade
CAS	6151-40-2
EINECS	628-688-3
化学式	C20H24N2O2.ClH.H2O
分子量	378.9
熔点	258-259 C
存储条件	2-8℃
体外研究	Quinidine hydrochloride monohydrate blocks WT mSlo3 (K Ca 5.1) channels with an IC 50 of 19.9±1.41 μM and Hill slope of 1.15±0.15 (n=7). Again, the potency of inhibition by Quinidine hydrochloride monohydrate is higher for F304Y mSlo3 (IC 50 of 2.42±0.60 μM, n=9, P<0.005; Hill slope of 0.98±0.12), but lower with R196Q mSlo3 (IC 50 of 38.4±6.77 μM, n=5, P<0.001; Hill slope of 1.05±0.16). The inhibition of F304Y mSlo3 by Quinidine hydrochloride monohydrate is observed to have some time dependence.
体内研究	Direct application of Quinidine hydrochloride monohydrate on the sciatic nerve produces a dose-related decrease in amplitude at ascending somato-sensory evoked potential (SSEP) and descending compound muscle action potentials (CMAP) when comparing baseline with other time points, or when comparing the experimental left limb to the right contra-lateral glucose-treated limb. The latencies of SSEPs and CMAP potentials after Quinidine hydrochloride monohydrate applications are increased compare to baseline and the contralateral side.
危险品标志	Xn - 有害物品 Xi - 刺激性物品
风险术语	R20/21/22 - 吸入、皮肤接触及吞食有害。 R36/37/38 - 刺激眼睛、呼吸系统和皮肤。
安全术语	S36 - 穿戴适当的防护服。 S26 - 不慎与眼睛接触后，请立即用大量清水冲洗并征求医生意见。
危险品运输编号	UN 2811 6.1/PG 3
WGK Germany	3

6151-40-2 - 配置溶液浓度参考

	1mg	5mg	10mg
1 mM	2.771 ml	13.855 ml	27.71 ml
5 mM	0.554 ml	2.771 ml	5.542 ml
10 mM	0.277 ml	1.386 ml	2.771 ml
5 mM	0.055 ml	0.277 ml	0.554 ml

最后更新：2024-01-02 23:10:35