黄杞苷,英文名:Engeletin,CAS:572-31-6,化学式:C21H22O10,分子量:434.39,密度:1.66,熔点:176-177℃,沸点:763.4±60.0 °C(Predict

2026-03-27 10:24:45

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572-31-6

黄杞苷(Engeletin)

CAS: 572-31-6

化学式: C21H22O10

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中文名	黄杞苷
英文名	Engeletin
别名	黄杞苷黄杞苷对照品, 黄杞苷(标准品) 黄杞苷, 来源于黄杞 ENGELETIN 黄杞苷二氢山柰酚-3-O-Α-L-鼠李糖苷
英文别名	Engeletin Engelitin AroMadendrin 3-rhaMnoside Dihydrokaempferol 3-rhamnoside Dihydrokaempferol 3-O-alpha-L-rhamnopyranoside (+)-(2R,3R)-Dihydrokaempferol 3-O-alpha-L-rhamnoside (2R,3R)-5,7-Dihydroxy-2-(4-hydroxyphenyl)-4-oxo-3,4-dihydro-2H-chromen-3-yl 6-deoxy-alpha-L-mannopyranoside (2R,3R)-5,7-dihydroxy-2-(4-hydroxyphenyl)-3-[(2S,3R,4R,5S,6S)-3,4,5-trihydroxy-6-methyl-oxan-2-yl]oxy-chroman-4-one 3-((6-Deoxy-alpha-L-Mannopyranosyl)oxy)-2,3-dihydro-5,7-dihydroxy-2-(4-hydroxyphenyl)-4H-1-benzopyran-4-one(2R-trans)
CAS	572-31-6
EINECS	300-009-2
化学式	C21H22O10
分子量	434.39
密度	1.66
熔点	176-177℃
沸点	763.4±60.0 °C(Predicted)
比旋光度	(Me2CO)-16
溶解度	易溶于沸水，溶于ＤＭＳＯ、热甲醇，几乎不溶于乙醚。
酸度系数	7.37±0.60(Predicted)
存储条件	2-8℃
外观	白色结晶
物化性质	类白色结晶性粉末，可溶于甲醇、乙醇、DMSO等有机溶剂，来源于土茯苓 Smilax glabra.菝葜。
MDL号	MFCD01632717
体外研究	Engeletin is a flavanonol glycoside isolated from hymenaea martiana , inhibits NF-κB signaling-pathway activation.
体内研究	Engeletin (25, 50, 100 mg/kg, i.p.) markedly reduces LPS-increased myeloperoxidase activity in mice, activates NF-κB-pathway activation, decreases the production of inflammatory mediators (iNOS and COX-2), and suppresses the expression of TLR4-signaling downstream molecules such as MyD88, IRAK1, TRAF6, and TAK1 proteins.
海关编号	29389090
参考资料展开查看	1. 刘丽娟,赵瑞芝,卢传坚.基于“药效-成分分析”的银屑灵优化方2号方抗银屑病配伍规律探讨[J].中华中医药杂志,2020,35(08):4171-4174. 2. 王梦雪,戴寒鹏,李金明,苏娅,韩欣然,李丽.土茯苓抑制CYP3A4酶活性的研究[J].长春师范大学学报,2020,39(08):60-63. 3. Guang Yang, Xin Zhao, Jun Wen, Tingting Zhou, Guorong Fan, Simultaneous fingerprint, quantitative analysis and anti-oxidative based screening of components in Rhizoma Smilacis Glabrae using liquid chromatography coupled with Charged Aerosol and Coulometric 4. [IF=4.192] Haichong Wu et al."Engeletin Alleviates Lipopolysaccharide-Induced Endometritis in Mice by Inhibiting TLR4-mediated NF-κB Activation."J Agr Food Chem. 2016;64(31):6171–6178 5. [IF=3.645] Weiquan Dai et al."Simultaneous chemical fingerprint and quantitative analysis of Rhizoma Smilacis Glabrae by accelerated solvent extraction and high-performance liquid chromatography with tandem mass spectrometry."J Sep Sci. 2015 May;38(9):1466-1475 6. [IF=4.098] Yangyang Fan et al."Interaction study of engeletin toward cytochrome P450 3A4 and 2D6 by multi-spectroscopy and molecular docking."Spectrochim Acta A. 2022 Jan;264:120311

572-31-6 - 简介

黄柏苷（也被称为黄杞苷）是一种天然存在的化合物，属于苷类化合物。它可以在黄杞树皮中找到。

黄柏苷具有许多药理活性，包括抗氧化、抗炎、抗菌和抗肿瘤等作用。
它被用作中药材，用于治疗炎症、感染和癌症等疾病。

黄柏苷的制法主要是通过提取黄杞树皮中的化合物得到。黄杞树皮被粉碎并经过溶剂提取。然后，通过柱层析、薄层层析和结晶等技术，将黄柏苷纯化和获取。

黄柏苷的安全信息：目前还没有报道其严重的副作用。对于任何化学物质的使用都需要谨慎和适度。最后更新：2024-04-09 21:54:55

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