Azeliragon (TTP488),英文名:1-PropanaMine, 3-[4-[2-butyl-1-[4-(4-chlorophenoxy)phenyl]-1H-iMidazol-4-yl]

603148-36-3 询问

Azeliragon (TTP488)(1-PropanaMine, 3-[4-[2-butyl-1-[4-(4-chlorophenoxy)phenyl]-1H-iMidazol-4-yl]phenoxy]-N,N-diethyl-)

CAS: 603148-36-3

化学式: C32H38ClN3O2

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中文名	Azeliragon (TTP488)
英文名	1-PropanaMine, 3-[4-[2-butyl-1-[4-(4-chlorophenoxy)phenyl]-1H-iMidazol-4-yl]phenoxy]-N,N-diethyl-
别名	阿齐瑞格 3-[4-[2-丁基-1-[4-... 3-[4-[2-丁基-1-[4-(4-氯苯氧基)苯基]-1H-咪唑]苯氧基]-N,N-二乙基-1-丙胺
英文别名	Azeliragon AZELIRAGON Azeliragon (TTP488) Azeliragon(PF-04494700,TTP488) 3--4--2-Butyl-1--4--4-chlorphenoxy-phenyl--1H-imidazol-4-yl-phenoxy--N-N-diethylpropan-1-amin 3-(4-(2-butyl-1-(4-(4-chlorophenoxy)phenyl)-1H-imidazol-4-yl)phenoxy)-N,N-diethylpropan-1-amine N-[3-[4-[2-Butyl-1-[4-(4-chlorophenoxy)phenyl]-1H-imidazol-4-yl]phenoxy]propyl]-N,N-diethylamine 1-PropanaMine, 3-[4-[2-butyl-1-[4-(4-chlorophenoxy)phenyl]-1H-iMidazol-4-yl]phenoxy]-N,N-diethyl-
CAS	603148-36-3
化学式	C32H38ClN3O2
分子量	532.12
密度	1.11±0.1 g/cm3(Predicted)
沸点	667.7±65.0 °C(Predicted)
酸度系数	10.16±0.25(Predicted)
存储条件	Room Temprature
体内研究	在阿尔茨海默症动物模型(tgAPPSwedish/London)中，azeliragon可减少Aβ斑块沉积、减少总的Aβ闹浓度而提高血浆中Aβ水平、降低sAPPβ而提升sAPPα水平、减少炎性细胞因子、减缓认知减退过程和改善脑血流量。

603148-36-3 - 配置溶液浓度参考

	1mg	5mg	10mg
1 mM	1.879 ml	9.396 ml	18.793 ml
5 mM	0.376 ml	1.879 ml	3.759 ml
10 mM	0.188 ml	0.94 ml	1.879 ml
5 mM	0.038 ml	0.188 ml	0.376 ml

最后更新：2024-01-02 23:10:35