3-Chloro-4-hydroxyphenylboronic acid pinacol ester, English name: 3-Chloro-4-hydroxyphenylboronic acid, pinacol ester, CAS: 629658-06-6, Chemical formula: C12H16BC
629658-06-6
3-Chloro-4-hydroxyphenylboronic acid pinacol ester (3-Chloro-4-hydroxyphenylboronic acid, pinacol ester)
CAS: 629658-06-6
Chemical formula: C12H16BClO3
<"" ="xl" "">| Chinese name | 3-Chloro-4-hydroxyphenylboronic acid pinacol ester |
| English name | 3-Chloro-4-hydroxyphenylboronic acid, pinacol ester |
| alias | 3-Chloro-4-hydroxyphenylboronic acid pinnitol ester 3-Chloro-4-hydroxyphenylboronic acid pinacol ester 2-Chloro-4- (4,4,5,5-tetramethyl-1,3,2-dioxaborane-2-yl) phenol |
| English alias | 3-Chloro-4-hydroxyphenylboronic acid, pinacol ester 2-chloro-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phen 2-Chloro-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenol Phenol, 2-chloro-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)- |
| CAS | 629658-06-6 |
| chemical formula | C12H16BClO3 |
| molecular weight | 254.52 |
| density | 1.19±0.1 g/cm3(Predicted) |
| Boiling Point | 350.8±32.0 °C(Predicted) |
| acidity coefficient | 8.18±0.35(Predicted) |
| storage conditions | 2-8°C |
629658-06-6 - brief introduction
The properties of this compound are as follows:
- Appearance: 3-Chloro-4-hydroxyphenylboronic acid pinacol ester is white crystal or white crystalline powder.
Solubility: 3-Chloro-4-hydroxyphenylborate is soluble in common organic solvents such as chlorinated hydrocarbons, ethers, and alcohols.
The main uses of 3-chloro-4-hydroxyphenylboronic acid pinacol ester include:
-Alcohol ester group: The alcohol ester group in this compound is an important functional group and has a wide range of applications in organic synthesis. It can be used as a reagent for bifunctional chemical reactions.
Palladium catalysis: 3-chloro-4-hydroxyphenylboronic acid pinacol ester can be used as a substrate or ligand for palladium-catalyzed reactions in C-C bond formation reactions and other organic reactions.
The preparation method of 3-chloro-4-hydroxyphenylboronic acid pinacol ester is as follows:
First, pinacol borate was obtained by the reaction of pinacol with boric acid, and then a hydrogen atom on pinacol was replaced by chlorination in the presence of chlorinated hydrocarbons to obtain 3-chloro-4-hydroxyphenylboronic acid pinacol ester.
Safety information for this compound: It is necessary to pay attention to the following points:
- 3-Chloro-4-hydroxyphenylboronic acid pinacol esters are organic compounds that are toxic to some extent. Appropriate personal protective equipment, including gloves, protective glasses, and laboratory clothing, is required when operating.
- Avoid inhalation, ingestion or contact with skin. Avoid reaction with strong oxidants or strong acids.
During use, maintain good ventilation in the work area and follow relevant safety operating procedures.
In summary, 3-chloro-4-hydroxyphenylboronic acid pinacol ester is an organic compound that is mainly used in organic synthesis reactions and requires compliance with relevant safety practices.Last Updated: 2024-04-10 22:29:15
