1-Boc-6-methylbenzimidazole-5-borate, English name: 1H-BenziMidazole-1-carboxylic acid, 6-Methyl-5- (4,4,5,5-tetraMethyl-1,3,2-d

2026-03-27 10:24:45

631912-39-5

1-Boc-6-Methylbenzimidazole-5-borate (1H-BenziMidazole-1-carboxylic acid, 6-Methyl-5- (4,4,5,5-tetraMethyl-1,3,2-dioxaborolan-2-yl) -, 1,1-diMethylethyl ester)

CAS: 631912-39-5

Chemical formula: C19H27BN2O4

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Chinese name 1-Boc-6-methylbenzimidazole-5-borate
English name 1H-BenziMidazole-1-carboxylic acid, 6-Methyl-5-(4,4,5,5-tetraMethyl-1,3,2-dioxaborolan-2-yl)-, 1,1-diMethylethyl ester
English alias 1-N-Boc-(6-Methyl-1H-1,3-benzodiazol-5-yl)boronic acid, pinacol ester
tert-Butyl 6-methyl-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-benzo[d]imidazole-1-car
tert-Butyl 6-methyl-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-benzo[d]imidazole-1-carbox
tert-Butyl 6-methyl-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-benzimidazole-1-carboxylate
tert-Butyl 6-methyl-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-benzo[d]imidazole-1-carboxylate
1H-BenziMidazole-1-carboxylic acid, 6-Methyl-5-(4,4,5,5-tetraMethyl-1,3,2-dioxaborolan-2-yl)-, 1,1-diMethylethyl ester
CAS 631912-39-5
chemical formula C19H27BN2O4
molecular weight 358.24
storage conditions 2-8°C

631912-39-5 - brief introduction

1-Boc-6-methylbenzimidazole-5-borate is an organic compound. It is a white crystalline solid with good solubility and is soluble in common organic solvents such as methanol, dimethylformamide and N, N-dimethylformamide.

This compound is commonly used in protecting group reactions in organic synthesis, and is stable and selective, capable of protecting amino groups (e.g. aniline) or hydroxyl groups.

The preparation of 1-Boc-6-methylbenzimidazole-5-borate is usually a two-step process. Benzimidazole is esterified with tert-butyl carbonate to obtain 1-Boc-6-methylbenzimidazole. It is then condensed with 4,4,5,5-tetramethyl-1,3,2-dioxane-pentadiene-borate (abbreviated as B2pin2) under basic conditions to form the target product.

Safety Information: 1-Boc-6-methylbenzimidazole-5-borate is less toxic, but basic laboratory practices still need to be followed. Pay attention to protective measures and avoid contact with skin and inhalation. If necessary, personal protective equipment such as chemical protective gloves and goggles should be used. When storing, avoid contact with oxidants and store in a dry, cool place.Last Updated: 2024-04-09 21:11:58
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