CID 2011756,英文名:5-(3-Chlorophenyl)-N-[4-morpholin-4-ymethyl)phenyl]furan-2-carboxamide,CAS:638156-11
638156-11-3
CID 2011756(5-(3-Chlorophenyl)-N-[4-morpholin-4-ymethyl)phenyl]furan-2-carboxamide)
CAS: 638156-11-3
Chemical formula: C22H21ClN2O3
<"" ="xl" "">| Chinese name | CID 2011756 |
| English name | 5-(3-Chlorophenyl)-N-[4-morpholin-4-ymethyl)phenyl]furan-2-carboxamide |
| alias | PKD1 inhibitors (CID 2011756) 5- (3-chlorophenyl) -N- (4- (morpholinomethyl) phenyl) furan-2-carboxylamide 5- (3-chlorophenyl) -N- [4- (4-morpholinyl methyl) phenyl] -2-furanoformamide 5- (3-Chlorophenyl) -N- [4- (4-morpholinyl methyl) phenyl] -2-furanoformamide (CID-2011756) |
| English alias | CID2011756 CID-2011756 CID 2011756 CID-2011756 5-(3-chlorophenyl)-N-(4-(MorpholinoMethyl)phenyl)furan-2-carboxaMide 5-(3-Chlorophenyl)-N-[4-morpholin-4-ymethyl)phenyl]furan-2-carboxamide 5-(3-Chlorophenyl)-N-[4-(4-morpholinylmethyl)phenyl]-2-furancarboxamide 5-(3-Chlorophenyl)-N-[4-(morpholin-4-ylmethyl)phenyl]furan-2-carboxamide CID-2011756,5-(3-chlorophenyl)-N-(4-(MorpholinoMethyl)phenyl)furan-2-carboxaMide |
| CAS | 638156-11-3 |
| EINECS | 804-083-1 |
| chemical formula | C22H21ClN2O3 |
| molecular weight | 396.87 |
| density | 1.297±0.06 g/cm3(Predicted) |
| Boiling Point | 491.0±45.0 °C(Predicted) |
| solubility | DMSO: Dissolve 10mg/mL (clear solution) |
| acidity coefficient | 12.54±0.70(Predicted) |
| storage conditions | room temp |
| stability | Stable for 1 year from the date of purchase provided. Solutions in DMSO or ethanol can be stored at -20 ° C for up to 3 months. |
| appearance | powder |
| color | white to beige |
| in vitro study | CID 2011756 is an ATP-competitive PKD1 inhibitor, with an IC 50 of 3.2 µM. CID 2011756 decreases the phosphorylation of endogenous PKD1 Ser 916 in LNCaP cancer cells with an EC 50 of 10±0.7 µM. CID 2011756 also has cellular pan-PKD inhibitory effects, with IC 50 s of 0.6±0.1 µM and 0.7±0.2 µM for PKD2 and PKD3, respectively. |
| Dangerous goods sign | Xn - Hazardous Items |
| Risk Terminology | R22 - Harmful if swallowed. R36 - Irritating to the eyes. |
| security terms | 26 - After accidental eye contact, rinse immediately with plenty of water and seek medical advice. |
| WGK Germany | 3 |
638156-11-3 - Configuration Solution Concentration Reference
| 1mg | 5mg | 10mg | |
|---|---|---|---|
| 1 mM | 2.52 ml | 12.599 ml | 25.197 ml |
| 5 mM | 0.504 ml | 2.52 ml | 5.039 ml |
| 10 mM | 0.252 ml | 1.26 ml | 2.52 ml |
| 5 mM | 0.05 ml | 0.252 ml | 0.504 ml |
638156-11-3 - brief introduction
CID 2011756 is a chemical compound with the chemical name 2-amino-2-methyl-1-butanone. The following is an introduction to the properties, uses, preparation methods and safety information of this compound:Properties: CID 2011756 is a solid substance with a white crystalline appearance. The compound is stable at room temperature and pressure, soluble in water and organic solvents.
Uses: CID 2011756 has a variety of uses in chemical research and industrial applications. One of them is as an intermediate in organic synthesis, participating in the synthesis of a variety of organic compounds.
Preparation method: The method of preparing CID 2011756 is more complicated. The common method is to obtain 2-amino-2-methyl-1-butanone by the reaction of methyl carbamate and sodium cyanide.
Safety Information: There is limited safety information about CID 2011756 and appropriate safety measures need to be taken when using or handling this substance. Personal protective equipment such as laboratory gloves, protective glasses and laboratory coats should be worn. Avoid inhalation, ingestion and contact with the skin to avoid causing adverse health effects. CID 2011756 should be stored in a dry, cool place and avoid contact with incompatible substances.Last Updated: 2024-04-09 20:52:54
