CAS number：131740-09-5 molecular formula：C21H20ClNO5.HCl
Product Describtion: Alvocidib Hydrochloride is a synthetic N-methylpiperidinyl chlorophenyl flavone compound. As an inhibitor of cyclin-dependent kinase, alvocidib induces cell cycle arrest by preventing phosphorylation of cyclin-dependent kinases (CDKs) and by down-regulating cyclin D1 and D3 expression, resulting in G1 cell cycle arrest and apoptosis. This agent is also a competitive inhibitor of adenosine triphosphate activity.
| Chinese alias | 夫拉平度盐酸盐 | ||
| English alias | 4H-1-BENZOPYRAN-4-ONE, 2-(2-CHLOROPHENYL)-5,7-DIHYDROXY-8-((3S,4R)-3-HYDROXY-1-METHYL-4-PIPERIDINYL)-, HYDROCHLORIDE (1:1) | BCP9000688 | rel-(-)-2-(2-Chlorophenyl)-5,7-dihydroxy-8-[(3S,4R)-3-hydroxy-1-methyl-4-piperidinyl]-4H-1-benzopyran-4-one Hydrochlo | ||
| CAS number | 131740-09-5 | molecular formula | C21H20ClNO5.HCl |
| molecular weight | 438.3 g/mol | Exact mass | - |
| PSA | 90.200 Ų | logp | - |
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