The product is a phosphinooxazoline (PHOX) ligand introduced by Pfaltz and coworkers. These non-symmetrical modular P,N-ligands are particularly useful in cases where double bond migration leads to undesired products or mixtures of isomers.(S)-4-tert-Butyl-2-[2-(diphenylphosphino)phenyl]-2-oxazoline can be used as a ligand for enantioselective Heck reaction without any C=C double bond migration byproduct. It can also be used in a rhodium(I)-catalyzed enantioselective desymmetrization reaction of meso-3,5-dimethyl glutaric anhydride, to form substituted syn-deoxypolypropionate fragments in a single transformation. The product is a phosphinooxazoline (PHOX) ligand introduced by Pfaltz and coworkers. These non-symmetrical modular P,N-ligands are particularly useful in cases where double bond migration leads to undesired products or mixtures of isomers.
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(S)-4-tert-Butyl-2-[2-(diphenylphosphino)phenyl]-2-oxazoline
Dangerous GoodsCAS number：148461-16-9 molecular formula：C25H26NOP
overview
compound introduction
Specs
| Chinese alias | (4S)-叔丁基-2-[2-(二苯基膦基)苯基]-4,5-二氢噁唑 | ||
| English alias | (4S)-4-tert-Butyl-2-[2-(diphenylphosphanyl)phenyl]-4,5-dihydro-1,3-oxazole | AKOS016845941 | DTXSID70433043 | MFCD09998277 | J-008473 | AS-72502 | [2-[(4S)-4-tert-butyl-4,5-dihydro-1,3-oxazol-2-yl]phenyl]-diphenylphosphane | SCHEMBL1111225 | (S)-4-(tert-B | ||
| CAS number | 148461-16-9 | molecular formula | C25H26NOP |
| molecular weight | 387.45 g/mol | Exact mass | ≥97% |
| PSA | 21.600 Ų | logp | 5.900 |
numbering system
No numbering system information yet
physicochemical properties
No physical and chemical property information yet
Safety information
Signal word：
Warning
Hazard Statement：
H315: 引起皮肤刺激 H319: 引起严重眼睛刺激 H335: 可能引起呼吸道刺激 H302: 吞食有害
Statement of Preventive Measures：
P261: 避免吸入灰尘/烟雾/气体/雾/蒸汽/喷雾 P305+P351+P338: 如进入眼睛：用水小心冲洗几分钟。如戴隐形眼镜并可方便地取出，取出隐形眼镜。继续冲洗。 P280: 戴防护手套/穿防护服/戴防护眼罩/戴防护面具。 P302+P352: 如皮肤沾染：用水充分清洗。 P301+P312: 如误吞咽：如感觉不适，呼叫急救中心/医生。
WGK Germany：
3
Personal protective equipment：
Eyeshields， Gloves， type N95 (US)， type P1 (EN143) respirator filter
Production methods and uses
No production method and use information yet
Related
upstream information
No upstream information yet
downstream information
No downstream information yet
MSDS
Found 1 shareMSDS
148461-16-9 | (S)-4-tert-Butyl-2-[2-(diphenylphosphino)phenyl]-2-oxazoline.pdf
