compound introduction
Lefamulin acetate (Xenleta, BC-3781 acetate) 是一种截短侧耳素抗生素，用于 community-acquired bacterial pneumonia (CABP) 的治疗。Lefamulin acetate 通过与50S bacterial ribosome 的肽基转移酶中心结合来抑制蛋白质合成，从而阻止了转移RNA与肽转移的结合。 Information Lefamulin acetate (Xenleta) Lefamulin acetate (Xenleta, BC-3781 acetate) is a pleuromutilin antibiotic for community-acquired bacterial pneumonia (CABP) treatment. Lefamulin acetate inhibits protein synthesis by binding to the peptidyl transferase center of the 50S bacterial ribosome , thus preventing the binding of transfer RNA for peptide transfer.
