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Pemrametostat (GSK3326595)

Dangerous Goods

CAS number：1616392-22-3    molecular formula：C24H32N6O3

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physicochemical properties
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overview

compound introduction

Pemrametostat (GSK3326595, EPZ015938)是一种具有口服活性的、有效的、选择性protein arginine methyltransferase 5 (PRMT5)抑制剂，在体内外有效地抑制肿瘤生长。 Information Pemrametostat (GSK3326595) Pemrametostat (GSK3326595, EPZ015938) is an orally active, potent and selective inhibitor of protein arginine methyltransferase 5 (PRMT5) and potently inhibits tumor growth in vitro and in vivo in animal models. Targets PRMT5

Specs

Chinese alias培美司他（GSK3326595）
English alias4-pyrimidinecarboxamide, 6-((1-acetyl-4-piperidinyl)amino)-N-(3-(3,4-dihydro-2(1H)-isoquinolinyl)-2-hydroxypropyl)- | BDBM178166 | GSK3326595? | NSC800404 | NSC-800404 | UNII-VXT8SZ6875 | (S)-6-((1-acetylpiperidin-4-yl)amino)-N-(3-(3,4-dihydroisoquinolin-
CAS number1616392-22-3molecular formulaC24H32N6O3
molecular weight452.55 g/molExact mass≥98%
PSA111.000 Ųlogp0.692

numbering system

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physicochemical properties

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Safety information

pictogram：
GHS07
Signal word：
Warning
Hazard Statement：
H315: 引起皮肤刺激 H319: 引起严重眼睛刺激 H335: 可能引起呼吸道刺激 H302: 吞食有害
Statement of Preventive Measures：
P261: 避免吸入灰尘/烟雾/气体/雾/蒸汽/喷雾 P305+P351+P338: 如进入眼睛：用水小心冲洗几分钟。如戴隐形眼镜并可方便地取出，取出隐形眼镜。继续冲洗。

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