PCI-34051

Dangerous Goods

CAS number：950762-95-5 molecular formula：C17H16N2O3

overview

Specs

numbering system

physicochemical properties

Safety information

Production methods and uses

MSDS

overview

compound introduction

PCI-34051是一种有效的，特异性的HDAC8抑制剂，无细胞试验中IC50为10 nM。比作用于HDAC1和6选择性高200多倍，比作用于HDAC2， 3，和10选择性高1000倍。A potent and specific HDAC8 inhibitor. PCI-34051 is a potent and specific HDAC8 inhibitor with IC50 of 10 nM in a cell-free assay. It has greater than 200-fold selectivity over HDAC1 and 6, more than 1000-fold selectivity over HDAC2, 3, and 10. A potent and specific HDAC8 inhibitor.

Specs

Chinese alias	-
English alias	N-hydroxy-1-[(4-methoxyphenyl)methyl]indole-6-carboxamide \| BP-12358 \| GKW \| BDBM50397360 \| CCG-267430 \| HMS3604D11 \| HY-15224 \| SB17080 \| BCP9001056 \| N-Hydroxy-1-[(4-methoxyphenyl)methyl]-1H-indole-6-carboxamide \| 1-[(4-methoxyphenyl)methyl]indole-6-car
CAS number	950762-95-5	molecular formula	C17H16N2O3
molecular weight	296.32 g/mol	Exact mass	≥98%
PSA	63.500 Å²	logp	2.400

numbering system

No numbering system information yet

physicochemical properties

No physical and chemical property information yet

Safety information

pictogram：

GHS07

Signal word：

Warning

Hazard Statement：

H319: 引起严重眼睛刺激 H302: 吞食有害

Statement of Preventive Measures：

P305+P351+P338: 如进入眼睛：用水小心冲洗几分钟。如戴隐形眼镜并可方便地取出，取出隐形眼镜。继续冲洗。 P280: 戴防护手套/穿防护服/戴防护眼罩/戴防护面具。 P501: 将内容物/容器处理到。。。 P264: 处理后要彻底洗手。 P270: 使用本产品时，请勿进食、饮水或吸烟。 P330: 漱口 P264+P265: 处理后彻底洗手[和…]。不要触摸眼睛。 P301+P317: 如果被吞咽：请寻求医疗帮助。 P337+P317: 如果眼睛刺激持续：寻求医疗帮助。