CAS number：859212-16-1 molecular formula：C30H31F3N8O
Bafetinib (INNO-406)是一种有效的，选择性的，Bcr-Abl/Lyn双重抑制剂，IC50为5.8 nM/19 nM，对T315I突变型的磷酸化没有抑制作用，对PDGFR和c-Kit的作用效果稍弱。 Bafetinib (INNO-406) is a potent and selective dual Bcr-Abl/Lyn inhibitor with IC50 of 5.8 nM/19 nM, does not inhibit the phosphorylation of the T315I mutant and is less potent to PDGFR and c-Kit.
| Chinese alias | 巴非替尼 | ||
| English alias | NS-187 | AS-13209 | BAFETINIB [MART.] | Bafetinib [USAN:INN] | (S)-N-(3-(4,5'-bipyrimidin-2-ylamino)-4-methylphenyl)-4-((3-(dimethylamino)pyrrolidin-1-yl)methyl)-3-(trifluoromethyl)benzamide | GS-3022 | NSC799354 | NSC-799354 | s1369 | 4-[[(3S)-3-(dimethy | ||
| CAS number | 859212-16-1 | molecular formula | C30H31F3N8O |
| molecular weight | 576.62 g/mol | Exact mass | - |
| PSA | 99.200 Ų | logp | 4.2 |
No numbering system information yet
No physical and chemical property information yet
No production method and use information yet
No upstream information yet
No downstream information yet
