compound introduction
Copanlisib (BAY 80-6946)是一个高效的泛I型 PI3K抑制剂，其对PI3Kα/β/γ/δ抑制的IC50分别为0.5, 3.7, 6.4, and 0.7 nM。
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BAY 80-6946 (Copanlisib)
Dangerous GoodsCAS number：1032568-63-0 molecular formula：C23H28N8O4
overview
Specs
| Chinese alias | - | ||
| English alias | COPANLISIB [USAN] | BAY 80-6946; Copanlisib | Copanlisib [USAN:INN] | 2-Chloro-11-(4-methylpiperazin-1-yl)dibenzo[b,f][1,4]oxazepinesuccinate | BRD-K07265709-003-01-5 | NSC800076 | s2802 | A907819 | HY-15346 | 1032568-63-0 | 5-PYRIMIDINECARBOXAMIDE, 2-AMI | ||
| CAS number | 1032568-63-0 | molecular formula | C23H28N8O4 |
| molecular weight | 480.52 g/mol | Exact mass | - |
| PSA | 140.000 Ų | logp | 0.3 |
numbering system
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physicochemical properties
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Safety information
pictogram：
GHS07
Signal word：
Warning
Hazard Statement：
H315: 引起皮肤刺激 H319: 引起严重眼睛刺激 H335: 可能引起呼吸道刺激
Statement of Preventive Measures：
P261: 避免吸入灰尘/烟雾/气体/雾/蒸汽/喷雾 P305+P351+P338: 如进入眼睛：用水小心冲洗几分钟。如戴隐形眼镜并可方便地取出，取出隐形眼镜。继续冲洗。
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MSDS
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