Nimbolide is a limonoid tetranortriterpenoid with an α,β-unsaturated ketone system and a δ-lactone ring. 添加Biochem/physiol ActionsNimbolide exhibits anti-malarial, anti-bacterial, and anti-cancer activities. It has been shown to induce apoptosis in osteosarcoma cells and inhibits cell migration of these cells by modulating the expression of integrin αvβ5. In human renal carcinoma cells, nimbolide induced cell cycle arrest, DNA damage, and apoptosis. Nimbolide is a triterpene isolated from Azadirachta indica. It has been shown to modulate autophagy and apoptosis in pancreatic cancer. Nimbolide is a limonoid tetranortriterpenoid with an α,β-unsaturated ketone system and a δ-lactone ring. 添加Biochem/physiol ActionsNimbolide exhibits anti-malarial, anti-bacterial, and anti-cancer activities. It has been shown to induce apoptosis in osteosarcoma cells and inhibits cell migration of these cells by modulating the expression of integrin αvβ5. In human renal carcinoma cells, nimbolide induced cell cycle arrest, DNA damage, and apoptosis. Nimbolide is a triterpene isolated from Azadirachta indica. It has been shown to modulate autophagy and apoptosis in pancreatic cancer.
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Nimbolide
Dangerous GoodsCAS number：25990-37-8 molecular formula：C27H30O7
overview
compound introduction
Specs
| Chinese alias | 印苦楝内酯 | (2aR,5aR,6S,6aR,8R,9aR,10aS,10bR,10cR)-8-(3-呋喃基)-2a,5a,6,6a,8,9,9a,10a,10b,10c-十氢-2a,5a,6a,7-四甲基-2,5-二羰基-2H,5H-环戊二烯并[d']萘并[1,8-bc:2,3-b']二呋喃-6-乙酸甲基酯 | ||
| English alias | F82256 | XN164985 | J-016215 | Methyl 2-[(1R,2S,4R,6R,9R,10S,11R,15R,18R)-6-(furan-3-yl)-7,9,11,15-tetramethyl-12,16-dioxo-3,17-dioxapentacyclo[9.6.1.02,9.04,8.015,18]octadeca-7,13-dien-10-yl]acetate | NCI60_002662 | FT-0672734 | MEGxp0_001495 | NSC309909 | ||
| CAS number | 25990-37-8 | molecular formula | C27H30O7 |
| molecular weight | 466.52 g/mol | Exact mass | ≥97% |
| PSA | 92.000 Ų | logp | 2.200 |
numbering system
No numbering system information yet
physicochemical properties
No physical and chemical property information yet
Safety information
pictogram：
GHS07
Signal word：
Warning
Hazard Statement：
H302: 吞食有害
Statement of Preventive Measures：
P501: 将内容物/容器处理到。。。 P264: 处理后要彻底洗手。 P270: 使用本产品时，请勿进食、饮水或吸烟。 P330: 漱口 P301+P317: 如果被吞咽：请寻求医疗帮助。
Production methods and uses
No production method and use information yet
Related
upstream information
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downstream information
No downstream information yet
MSDS
Found 1 shareMSDS
25990-37-8 | Neem Lactone | Nimbolide
