CAS number：1515888-53-5 molecular formula：C26H25N5O
Information UCB-9260 UCB-9260 is an orally active inhibitor that inhibits TNF signalling by stabilising an asymmetric form of the trimer. UCB-9260 binds TNF with Kd of 13 nM. UCB-9260 also inhibits NF-κB with IC50 of 202 nM after TNF stimulation. Targets TNF (Cell-free assay); NF-κB (Cell-free assay) 13 nM(Kd); 202 nM
| Chinese alias | - | ||
| English alias | 1H-Benzimidazole-2-methanol,1-[(2,5-dimethylphenyl)methyl]-6-(1-methyl-1H-pyrazol-4-yl)-α-4-pyridinyl- | ||
| CAS number | 1515888-53-5 | molecular formula | C26H25N5O |
| molecular weight | 423.51 g/mol | Exact mass | ≥99% |
| PSA | 68.800 Ų | logp | 4.432 |
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