AT-56 是一种有效,选择性和具有口服活性的脂钙蛋白型前列腺素 D 合酶 (L-PGDS) 的抑制剂,IC50 值为 95 μM,Ki 值为 75 μM。AT-56 可选择性抑制 L-PGDS 催化的 PGD2 介导的嗜睡或疼痛反应。
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AT-56
Dangerous GoodsCAS number:162640-98-4 molecular formula:C25H27N5
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compound introduction
Specs
| Chinese alias | - | ||
| English alias | BCP08667 | J-009959 | EX-A272 | FT-0700233 | MFCD18086874 | 4-(5H-Dibenzo[a,d]cyclohepten-5-ylidene)-1-[4-(2H-tetrazol-5-yl)butyl]-piperidine | AS-16433 | AKOS024457667 | 1-[4-(2H-tetrazol-5-yl)butyl]-4-(2-tricyclo[9.4.0.03,8]pentadeca-1(15),3,5,7,9,11,13 | ||
| CAS number | 162640-98-4 | molecular formula | C25H27N5 |
| molecular weight | 397.52 g/mol | Exact mass | - |
| PSA | 57.700 Ų | logp | 4.900 |
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WGK Germany:
3
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