3-O-Methylquercetin可抑制总 cAMP 和cGMP-phosphodiesterase (PDE)。它对PDE1、PDE5、PDE 和PDE4的IC50分别是31.9 μM、86.9 μM、18.6 μM 和1.6 μM。 生化/生理作用 3-O-甲基槲皮素能显著抑制环状单磷酸腺苷（cAMP-）和环状单磷酸鸟苷（cGMP-）磷酸二酯酶活性。它具有抗炎、抗支气管扩张的特性，可用于治疗哮喘。它抑制总的炎症细胞、肿瘤坏死因子-α（TNF-α），并减弱白介素的产生。 3-O-甲基槲皮素是黄酮和黄酮生物合成中的代谢产物，具有强大的抗癌、抗氧化、抗过敏和抗微生物活性，对番茄环斑病毒具有很强的抗病毒活性。 Biochem/physiol Actions 3-O-Methylquercetin significantly inhibits cyclic adenosine monophosphate- (cAMP-) and cyclic guanosine monophosphate- (cGMP-) phosphodiesterase activity. It possess anti-inflammatory, bronchodilating properties and used in treatment of asthma. It suppresses the total inflammatory cells, tumor necrosis factor-α (TNF-α) and attenuates the production of interleukins. 3-O-Methylquercetin is a metabolite in flavone and flavonol biosynthesis.It was shown to have potent anticancer-promoting, antioxidant, antiallergy, and antimicrobial activity[6], and showed strong anti-viral activity inhibition of tomato ringspot virus.
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3-O-Methylquercetin
Dangerous GoodsCAS number：1486-70-0 molecular formula：C16H12O7
overview
compound introduction
Specs
| Chinese alias | 5,7,3′ ,4′ -四羟基-3-甲氧基黄酮 | 槲皮素3-O-甲醚 | ||
| English alias | - | ||
| CAS number | 1486-70-0 | molecular formula | C16H12O7 |
| molecular weight | 316.26 g/mol | Exact mass | - |
| PSA | 116.000 Ų | logp | 2.500 |
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Safety information
pictogram：
GHS06
Signal word：
Danger
Hazard Statement：
H301: 吞咽会中毒
Statement of Preventive Measures：
P321: 特殊处理（请参阅此标签上的...）。 P405: 密闭存放 P501: 将内容物/容器处理到。。。 P264: 处理后要彻底洗手。 P270: 使用本产品时，请勿进食、饮水或吸烟。 P330: 漱口 P301+P316: 如果吞咽：立即寻求紧急医疗救助。
WGK Germany：
3
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