CAS number：97534-21-9 molecular formula：C11H9N3O3S
Merbarone (NSC 336628)是一种具有口服活性的拓扑异构酶II(topoisomerase II) 抑制剂。Merbarone的主要作用是阻断拓扑异构酶II介导的 DNA切割，而不会稳定拓扑II-DNA 共价复合物。Merbarone具有抗肿瘤功效。 Merbarone (NSC 336628) is an orally active inhibitor of topoisomerase II. Merbarone acts primarily by blocking topoisomerase II-mediated DNA cleavage without stabilizing topo II-DNA covalent complexes. Merbarone is an anticancer agent.
| Chinese alias | 梅尔巴罗内 | ||
| English alias | MS-23710 | NCGC00165827-01 | CCRIS 8215 | FT-0630995 | UNII-YWB9IF596V | BDBM241949 | 4,6-dioxo-N-phenyl-2-thioxohexahydropyrimidine-5-carboxamide | AKOS040748903 | NSC 336628 | 5-Pyrimidinecarboxamide, hexahydro-4,6-dioxo-N-phenyl-2-thioxo- | HEXAHYDRO-4 | ||
| CAS number | 97534-21-9 | molecular formula | C11H9N3O3S |
| molecular weight | 263.27 g/mol | Exact mass | ≥98% |
| PSA | 119.000 Ų | logp | 0.100 |
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