2'-（4-甲基伞形酮）-α

2′-(4-甲基伞形酮辛酸酯)-α-D-N-乙酰神经氨酸或 4-MUNANA 用作底物，以开发基于微孔板的神经氨酸酶抑制剂检测。 荧光底物2ʹ-(4-甲基伞形酮辛酸酯)-α-D-N-乙酰神经氨酸（4-MUNANA）用于研究阿司匹林和塞来昔布靶向哺乳动物神经氨酸酶-1 的分子机制。应用： 2′-(4-甲基伞形酮辛酸酯)-α-D-N-乙酰神经氨酸或 4-MUNANA 是一种合成荧光底物，模仿天然存在的神经氨酸酶底物。 酶-底物水解产生4-甲基伞形酮（4-MU），通过荧光法测定。 2′-(4-Methylumbelliferyl)-α-D-N-acetylneuraminic acid or 4-MUNANA is a synthetic fluorometric substrate that mimics the naturally occurring neuraminidase enzyme substrate. The enzyme-substrate hydrolysis results in the product 4-methylumbelliferone (4-MU), measured fluorometrically. Application: 2′-(4-Methylumbelliferyl)-α-D-N-acetylneuraminic acid or 4-MUNANA is used as a substrate for the development of a microplate-based assay for neuraminidase inhibitors. The fluorogenic substrate 2ʹ-(4-methylumbelliferyl)-α-D-N-acetylneuraminic acid (4-MUNANA) is used to study the molecular mechanisms of aspirin and celecoxib targeting mammalian neuraminidase-1.

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