compound introduction
Piclamilast (RP 73401) 是有效的磷酸二酯酶 4 (PDE4) 的抑制剂，其在猪主动脉和可溶性嗜酸性粒细胞中的 IC50 值分别为 16 nM 和 2 nM。
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Piclamilast
Dangerous GoodsCAS number：144035-83-6 molecular formula：C18H18Cl2N2O3
overview
Specs
| Chinese alias | 3-(环戊氧基)-N-(3,5-二氯-4-吡啶基)-4-甲氧基苯甲酰胺 | ||
| English alias | NCGC00371037-01 | Piclamilast | SCHEMBL26573 | A928568 | SR-01000945166-1 | EN300-133366 | Piclamilast [INN] | UNII-WM58D7C3ZT | 3-(Cyclopentyloxy)-N-(3,5-dichloro-4-pyridinyl)-4-methoxybenzamide | Benzamide, 3-(cyclopentyloxy)-N-(3,5-dichloro-4-pyridinyl | ||
| CAS number | 144035-83-6 | molecular formula | C18H18Cl2N2O3 |
| molecular weight | 381.25 g/mol | Exact mass | - |
| PSA | 60.500 Ų | logp | 4.200 |
numbering system
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physicochemical properties
No physical and chemical property information yet
Safety information
pictogram：
GHS07
Signal word：
Warning
Hazard Statement：
H315: 引起皮肤刺激 H319: 引起严重眼睛刺激 H335: 可能引起呼吸道刺激
Statement of Preventive Measures：
P261: 避免吸入灰尘/烟雾/气体/雾/蒸汽/喷雾 P305+P351+P338: 如进入眼睛：用水小心冲洗几分钟。如戴隐形眼镜并可方便地取出，取出隐形眼镜。继续冲洗。 P280: 戴防护手套/穿防护服/戴防护眼罩/戴防护面具。 P302+P352: 如皮肤沾染：用水充分清洗。 P321: 特殊处理（请参阅此标签上的...）。 P405: 密闭存放 P501: 将内容物/容器处理到。。。 P264: 处理后要彻底洗手。 P271: 仅在室外或通风良好的地方使用。 P304+P340: 如误吸入：将人转移
Production methods and uses
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Related
upstream information
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downstream information
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MSDS
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