AEG3482 是一种有效的抗凋亡化合物,可诱导热休克蛋白 70 (HSP70) 的表达来抑制 JNK 活性。AEG3482 通过直接结合 HSP90,从而促进 HSP70 和 HSP25 的 HSF1 依赖性表达。
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AEG 3482
Dangerous GoodsCAS number:63735-71-7 molecular formula:C10H8N4O2S2
overview
compound introduction
Specs
| Chinese alias | 6-苯基咪唑并[2,1-b] -1,3,4-噻二唑-2-磺酰胺 | ||
| English alias | 6-phenylimidazo[2,1-b][1,3,4]thiadiazole-2-sulfonamide | NCGC00167812-02 | Q27195229 | NCGC00167812-06 | Oprea1_698164 | SCHEMBL2540289 | 7EZF1A283N | HMS3677N15 | BCP01890 | CCG-221955 | NCGC00167812-01 | HY-107599 | AEG3482 | AEG-3482 | HMS1538B12 | Imi | ||
| CAS number | 63735-71-7 | molecular formula | C10H8N4O2S2 |
| molecular weight | 280.33 g/mol | Exact mass | ≥99%(HPLC) |
| PSA | 127.000 Ų | logp | 1.400 |
numbering system
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physicochemical properties
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Safety information
Hazard Statement:
H302: 吞食有害
WGK Germany:
3
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