CAS number：128311-08-0 molecular formula：C14H18Cl2N2O
Information (S)-PNU-282987 is the absolute stereochemistry form of PNU-282987. PNU 282987 is a potent agonist of α7-containing neuronal nicotinic acetylcholine receptors (nAChRs) with Ki of 26 nM for the rat receptor. PNU 282987 has negligible activity against α1β1γδ and α3β4 nAChRs as well as a panel of monoamine, muscarinic, glutamate, and GABA receptors, except 5-HT3 with Ki of 930 nM.
| Chinese alias | - | ||
| English alias | MFCD32182633 | SCHEMBL9601902 | PNU-282987 S enantiomer hydrochloride | HY-12560C | AKOS040745070 | N-[(3S)-1-Azabicyclo[2.2.2]octan-3-yl]-4-chlorobenzamide;hydrochloride | (S)-PNU-282987 (hydrochloride) | D81454 | Benzamide, N-1-azabicyclo[2.2.2]oct-3-yl | ||
| CAS number | 128311-08-0 | molecular formula | C14H18Cl2N2O |
| molecular weight | 301.2 g/mol | Exact mass | - |
| PSA | - | logp | - |
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