PD153035 HCl

Dangerous Goods

CAS number：183322-45-4 molecular formula：C16H14BrN3O2·HCl

overview

Specs

numbering system

physicochemical properties

Safety information

Production methods and uses

MSDS

overview

compound introduction

PD153035 HCl是一种有效的，特异性的EGFR抑制剂，Ki和IC50分别为5.2 pM和29 pM；对PGDFR， FGFR， CSF-1，InsR和Src几乎无作用。A potent inhibitor of epidermal growth factor (EGF) receptor tyrosine kinase PD153035 is a potent and specific inhibitor of EGFR with Ki and IC50 of 5.2 pM and 29 pM; little effect noted against PGDFR, FGFR, CSF-1, InsR and Src. A potent inhibitor of epidermal growth factor (EGF) receptor tyrosine kinase

Specs

Chinese alias	-
English alias	J-518170 \| s1079 \| N-(3-bromophenyl)-6,7-dimethoxyquinazolin-4-aminium chloride \| SR-01000597835 \| BS-16156 \| ZM252868 \| PD153035 HCl (SU-5271, AG1517) \| PD153035 (Hydrochloride);SU-5271 (Hydrochloride); AG1517 (Hydrochloride); ZM 252868 (Hydrochloride) \|
CAS number	183322-45-4	molecular formula	C16H14BrN3O2·HCl
molecular weight	396.67 g/mol	Exact mass	≥98%(HPLC)
PSA	56.300 Å²	logp	-

numbering system

No numbering system information yet

physicochemical properties

No physical and chemical property information yet

Safety information

pictogram：

GHS06 , GHS05 , GHS07

Signal word：

Danger

Hazard Statement：

H315: 引起皮肤刺激 H335: 可能引起呼吸道刺激 H301: 吞咽会中毒 H318: 造成严重的眼睛损伤

Statement of Preventive Measures：

P261: 避免吸入灰尘/烟雾/气体/雾/蒸汽/喷雾 P280: 戴防护手套/穿防护服/戴防护眼罩/戴防护面具。 P302+P352: 如皮肤沾染：用水充分清洗。 P321: 特殊处理（请参阅此标签上的...）。 P405: 密闭存放 P501: 将内容物/容器处理到。。。 P264: 处理后要彻底洗手。 P271: 仅在室外或通风良好的地方使用。 P270: 使用本产品时，请勿进食、饮水或吸烟。 P304+P340: 如误吸入：将人转移到空气新鲜处，保持呼吸舒适体位。 P403+P233: 存放在通风良

WGK Germany：