Vodobatinib (K0706)

Dangerous Goods

CAS number：1388803-90-4 molecular formula：C27H20ClN3O2

overview

Specs

numbering system

physicochemical properties

Safety information

Production methods and uses

MSDS

overview

compound introduction

Vodobatinib (K0706) 是一种有效的第三代，且具有口服活性的 Bcr-Abl1 酪氨酸激酶抑制剂，IC50 为 7 nM。Vodobatinib 对大多数 BCR-ABL1 点突变体具有活性，对 BCR-ABL1T315I 无活性。 Vodobatinib 可用于慢性粒细胞白血病 (CML) 研究。 Product description： Vodobatinib (K0706) is a potent, third generation and orally active Bcr-Abl1 tyrosine kinase inhibitor with an IC50 of 7 nM. Vodobatinib exhibits activity against most BCR-ABL1 point mutants, and has no activity against BCR-ABL1T315I. Vodobatinib can be used for chronic myeloid leukemia (CML) research

Specs

Chinese alias	-
English alias	4-METHYL-3-QUINOLIN-3-YL-ETHYNYL BENZOIC ACID N'-(2-CHLORO-6-METHYLBENZOYL)HYDRAZIDE \| 4-Methyl-3-quinolin-3-ylethynylbenzoic acid N'-(2-chloro-6-methylbenzoyl) hydrazide \| VODOBATINIB [WHO-DD] \| F88789 \| Vodobatinib [USAN] \| K0706 \| K-0706 \| NORETHISTERO
CAS number	1388803-90-4	molecular formula	C27H20ClN3O2
molecular weight	453.9 g/mol	Exact mass	-
PSA	71.100 Å²	logp	6

numbering system

No numbering system information yet

physicochemical properties

No physical and chemical property information yet

Safety information

pictogram：

GHS07

Signal word：

Warning

Hazard Statement：

H315: 引起皮肤刺激 H319: 引起严重眼睛刺激

Statement of Preventive Measures：

P305+P351+P338: 如进入眼睛：用水小心冲洗几分钟。如戴隐形眼镜并可方便地取出，取出隐形眼镜。继续冲洗。 P280: 戴防护手套/穿防护服/戴防护眼罩/戴防护面具。 P302+P352: 如皮肤沾染：用水充分清洗。 P264: 处理后要彻底洗手。 P337+P313: 如仍觉眼刺激：求医/就诊。 P362+P364: 脱掉沾污的衣服，清洗后方可重新使用。 P332+P313: 如发生皮肤刺激：求医/就诊。