PF-06447475 is a highly potent, selective, brain penetrant LRRK2 kinase inhibitor with IC 50 values of 3 nM and 11 nM for WT LRRK and G2019S LRRK2 , respectively. PF-06447475 can be used for parkinson's disease (PD) research. Form:Solid
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PF-06454589
Dangerous GoodsCAS number:1527473-30-8 molecular formula:C14H16N6O
overview
compound introduction
Specs
| Chinese alias | - | ||
| English alias | BDBM50059307 | compound 28 [PMID: 25353650] | 1527473-30-8 | HY-112855 | BCP30270 | PF-06454589 | Q27088323 | 4-(5-(1-methyl-1H-pyrazol-4-yl)-7H-pyrrolo[2,3-d]pyrimidin-4-yl)morpholine | AC-35574 | AKOS040759238 | EX-A2017 | 5-(1-methyl-1H-pyrazol-4-yl)-4 | ||
| CAS number | 1527473-30-8 | molecular formula | C14H16N6O |
| molecular weight | 284.32 g/mol | Exact mass | ≥99% |
| PSA | 71.900 Ų | logp | 0.700 |
numbering system
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physicochemical properties
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Safety information
pictogram:
GHS07
Signal word:
Warning
Hazard Statement:
H302: 吞食有害
Statement of Preventive Measures:
P501: 将内容物/容器处理到。。。 P264: 处理后要彻底洗手。 P270: 使用本产品时,请勿进食、饮水或吸烟。 P330: 漱口 P301+P317: 如果被吞咽:请寻求医疗帮助。
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