compound introduction
Mifobate (SR-202) 是一种有效且特异性的 PPARγ 拮抗剂，可选择性的抑制噻唑烷二酮 (TZD) 诱导的PPARγ转录活性 (IC50=140 μM)。Mifobate不影响 PPARα，PPARβ 或 FXR 的基础或配体刺激的转录活性。Mifobate具有抗肥胖和抗糖尿病作用。
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SR 202
Dangerous GoodsCAS number：76541-72-5 molecular formula：C11H17ClO7P2
overview
Specs
| Chinese alias | (4-氯苯基)(二甲氧基膦基)甲基磷酸二甲酯 | ||
| English alias | [(4-chlorophenyl)-dimethoxyphosphorylmethyl] dimethyl phosphate | Dimethyl .alpha.-(dimethoxyphosphinyl)-p-chlorobenzyl phosphate | Dimethyl (alpha-dimethoxyphosphinyl-p-chlorobenzyl) phosphate | SR-202 | Mifobate (USAN/INN) | MIFOBATE [INN] | AKOS0050674 | ||
| CAS number | 76541-72-5 | molecular formula | C11H17ClO7P2 |
| molecular weight | 358.65 g/mol | Exact mass | ≥98% |
| PSA | 80.300 Ų | logp | 1.000 |
numbering system
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physicochemical properties
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Safety information
WGK Germany：
2
Personal protective equipment：
Eyeshields， Gloves， type N95 (US)， type P1 (EN143) respirator filter
RTECS：
TB8817000
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MSDS
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