（S）-腺苷环3'，5'-（硫代磷酸氢根）三乙铵是cAMP依赖性蛋白激酶（PKA）（cAMP激动剂）的激活剂。与N6，O2'-二丁酰腺苷3'，5'-环一磷酸（dibutyryl-cAMP）或8-溴腺苷-3'，5'-环一磷酸（8-Br-cAMP）相比，对环状核苷酸依赖性磷酸二酯酶的抵抗力高得多）。没有新陈代谢的副作用，并且在许多生物系统中都是膜可渗透的。也建议作为Epac的激活剂（cAMP调节的鸟嘌呤核苷酸交换因子）。 (S)-Adenosine, cyclic 3',5'-(hydrogenphosphorothioate) triethylammonium is an activator of cAMP-dependent protein kinase (PKA) (cAMP agonist). Considerably higher resistance against cyclic nucleotide-dependent phosphodiesterases as compared to N6,O2'-dibutyryladenosine 3',5'-cyclic monophosphate (dibutyryl-cAMP) or 8-bromoadenosine-3',5'-cyclic monophosphate (8-Br-cAMP). There are no metabolic side effects and it is membrane permeable in many biological systems. Also suggested as an activator of Epac (cAMP-regulated guanine nucleotide exchange factor).
All
Chemical Reagents
Biomedicine
Organic raw materials
Inorganic chemical industry
intermediate
Agricultural chemicals
Auxiliaries and catalysts
Fragrances and Flavors
Dyes and Pigments
Daily chemical industry
(S)-Adenosine, cyclic 3′,5′-(hydrogenphosphorothioate) triethylammonium
CAS number：71774-13-5 molecular formula：C10H12N5O5PS
overview
compound introduction
Specs
| Chinese alias | - | ||
| English alias | (RP)-Camps | Rp-Adenosine 3',5'-cyclic Monophosphorothioate, Sodium Salt | p-Adenosine 3',5'-cyclic phosphorothiate | SCHEMBL22370431 | HY-100530A | RP-cAMPS | RP-Camp-S | AKOS040749365 | GTPL10392 | (Rp)-adenosine-3',5'-cyclic monophosphorothioate | Aden | ||
| CAS number | 71774-13-5 | molecular formula | C10H12N5O5PS |
| molecular weight | 345.27 g/mol | Exact mass | ≥98% |
| PSA | 170.000 Ų | logp | -0.800 |
numbering system
No numbering system information yet
physicochemical properties
No physical and chemical property information yet
Safety information
RTECS：
AU7358160
Production methods and uses
No production method and use information yet
Related
upstream information
No upstream information yet
downstream information
No downstream information yet
MSDS
Found 0 shareMSDS
