CJ-13,610 是一种具有口服活性的非氧化还原型 5-脂氧合酶 (5-LOX) 抑制剂。 CJ-13,610 抑制白三烯 B4 的生物合成并调节巨噬细胞中 IL-6 mRNA 的表达。 CJ-13,610 is an orally active and nonredox-type inhibitor of 5-lipoxygenase (5-LOX). CJ-13,610 inhibits the biosynthesis of leukotriene B4 and regulates the expression of IL-6 mRNA in macrophages. Application: CJ-13610 may be used to study 5-lipoxygenase-mediated cell signaling.
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CJ13610
Dangerous GoodsCAS number:179420-17-8 molecular formula:C22H23N3O2S
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| Chinese alias | CJ-13,610 | CJ-13610 | ||
| English alias | 2H-Pyran-4-carboxamide, tetrahydro-4-[3-[[4-(2-methyl-1H-imidazol-1-yl)phenyl]thio]phenyl]- | 4-(3-{[4-(2-methyl-1H-imidazol-1-yl)phenyl]sulfanyl}phenyl)tetrahydro-2H-pyran-4-carboxamide | 4-{3-[4-(2-Methyl-imidazol-1-yl)-phenylsulfanyl]-phenyl}-tetrahydr | ||
| CAS number | 179420-17-8 | molecular formula | C22H23N3O2S |
| molecular weight | 393.50 g/mol | Exact mass | - |
| PSA | 95.400 Ų | logp | 3.200 |
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