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VU 0357017 Hydrochloride

Dangerous Goods

CAS number：1135242-13-5    molecular formula：C18H27N3O3 · HCl

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overview

compound introduction

VU0357017 hydrochloride (CID-25010775) 是一种有效、选择性和可透过血脑屏障的 M1 毒蕈碱乙酰胆碱受体变构激动剂，EC50 值为 477 nM。VU0357017 hydrochloride 对 M1 具有高度选择性，在测试的最高浓度 (30μM) 下，在M2-M5处没有活性。VU0357017 hydrochloride 可用于阿尔茨海默症和精神分裂症的研究。 VU0357017 hydrochloride (CID-25010775) is a potent, selective and brain-penetrant allosteric agonist of M1 muscarinic acetylcholine receptor, with an EC50 of 477 nM. VU0357017 hydrochloride is highly selective for M1 and has no activity at M2-M5 up to the highest concentrations tested (30 μM). VU0357017 hydrochloride can be used for the research of Alzheimer’s disease and schizophrenia。

Specs

Chinese alias盐酸 VU 0357017 | 4-((2-(2-甲基苯甲酰氨基)乙基)氨基)哌啶-1-羧酸乙酯盐酸盐 | VU 0357017 盐酸盐
English aliasEX-A1757 | N-ACETYL PROCAINAMIDE(<30%) | Ethyl 4-{[2-(2-methylbenzamido)ethyl]amino}piperidine-1-carboxylate--hydrogen chloride (1/1) | J-002978 | VU0357017 | 4-[[2-[(2-methylbenzoyl)amino]ethyl]amino]-1-piperidinecarboxylic acid ethyl ester, monohydrochl
CAS number1135242-13-5molecular formulaC18H27N3O3 · HCl
molecular weight369.89 g/molExact mass≥98%(HPLC)
PSA70.700 Ųlogp-

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physicochemical properties

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Safety information

Signal word：
Warning
Hazard Statement：
H315: 引起皮肤刺激 H319: 引起严重眼睛刺激 H335: 可能引起呼吸道刺激 H302: 吞食有害
Statement of Preventive Measures：
P261: 避免吸入灰尘/烟雾/气体/雾/蒸汽/喷雾 P305+P351+P338: 如进入眼睛：用水小心冲洗几分钟。如戴隐形眼镜并可方便地取出，取出隐形眼镜。继续冲洗。
WGK Germany：
2

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