应用 三氟甲磺酸四（吡啶）铜（II）可用于催化：烯丙基氨基甲酸酯和苯乙烯的分子内和分子间叠氮化。芳基硼酸酯的18F-氟化，以生成可用作放射性示踪剂的氟代芳烃。芳基硼与放射性溴离子的亲核放射性溴化，从而用于放射性溴化药物的制备。四（吡啶）铜（II）三氟甲磺酸酯[Cu(OTf)2(py)4] 是一种常用的铜基催化剂。它通常用于催化铜介导的芳烃和杂芳烃的放射氟化。它还用于 2-氨基-N，N-二烷基苯甲酰胺的 C（sp3）-H 官能化/环化，合成 2,3-二取代-4（H）-喹唑啉酮。 Description Tetrakis(pyridine)copper(II) triflate [Cu(OTf)2(py)4] is a general copper-based catalyst. It is commonly used to catalyze copper-mediated radiofluorination of arenes and heteroarene. It is also employed in C(sp3)-H functionalization/cyclisation of 2-amino-N,N-dialkylbenzamides to synthesize 2,3-disubstituted-4(3H)-quinazolinones.Tetrakis(pyridine)copper(II) triflate can be used to catalyze:Intra and intermolecular aziridination of allylic carbamates and styrenes.18F-fluorination of aryl boronic esters to generate fluroarenes applicable as radiotracers.Nucleophilic radiobromination of aryl borons with a radiobromide ion applicable in the preparation of radiobrominated pharmaceuticals.
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Tetrakis(pyridine)copper(II) triflate
Dangerous GoodsCAS number：113110-58-0 molecular formula：C22H20CuF6N4O6S2
overview
compound introduction
Specs
| Chinese alias | Cu(吡啶)4(OTF)2 | 四(吡啶)铜(II)双(三氟甲磺酸盐) | ||
| English alias | Cu(pyridine)₄(OTf)₂ | [Cu(OTf)₂(py)₄] | Tetrakis(pyridine)copper(II) bis(trifluoromethanesulfonate) | ||
| CAS number | 113110-58-0 | molecular formula | C22H20CuF6N4O6S2 |
| molecular weight | 678.08 g/mol | Exact mass | ≥95% |
| PSA | - | logp | - |
numbering system
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physicochemical properties
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Safety information
pictogram：
GHS05
Signal word：
Danger
Hazard Statement：
H314: 造成严重的皮肤灼伤和眼睛损伤
Statement of Preventive Measures：
P305+P351+P338: 如进入眼睛：用水小心冲洗几分钟。如戴隐形眼镜并可方便地取出，取出隐形眼镜。继续冲洗。 P280: 戴防护手套/穿防护服/戴防护眼罩/戴防护面具。 P405: 密闭存放 P501: 将内容物/容器处理到。。。 P264: 处理后要彻底洗手。 P260: 不要吸入灰尘/烟雾/气体/雾/蒸汽/喷雾。 P303+P361+P353: 如皮肤（或头发）沾染：立即脱掉所有沾染的衣服。用水清洗皮肤/淋浴。 P301+P330+P331: 如误吞咽：漱口。不要诱导呕吐。 P304+P340
UN Number：
1759
Production methods and uses
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MSDS
Found 1 shareMSDS
113110-58-0 | Tetrakis(pyridine)copper(II) triflate.pdf
