Salinomycin sodium salt

Dangerous Goods

CAS number：55721-31-8 molecular formula：C42H69NaO11

overview

Specs

numbering system

physicochemical properties

Safety information

Production methods and uses

MSDS

overview

compound introduction

Salinomycin sodium salt (Sodium salinomycin) 是钾离子载体抗生素，是作用于 Wnt/Fzd/LRP 复合物的Wnt/β-catenin 信号传导抑制剂，能阻断 Wnt 诱导的 LRP6 磷酸化，导致 LRP6 蛋白降解。它选择性抑制人肿瘤干细胞。 Salinomycin sodium salt (Salinomycin sodium), an antibiotic potassium ionophore, is a potent inhibitor of Wnt/β-catenin signaling. Salinomycin sodium salt (Salinomycin sodium) acts on the Wnt/Fzd/LRP complex, blocks Wnt-induced LRP6 phosphorylation, and causes degradation of the LRP6 protein. Salinomycin sodium salt (Salinomycin sodium) shows selective activity against human cancer stem cells.

Specs

Chinese alias	-
English alias	NCGC00095055-01 \| (2R)-2-[(2R,5S,6R)-6-[(3S,5S,7R,9S,10S,12R,15R)-3-[(2R,5R,6S)-5-Ethyl-5-hydroxy-6-methyloxan-2-yl]-15-hydroxy-3,10,12-trimethyl-4,6,8-trioxadispiro[4.1.5.3]pentadec-13-en-9-yl]-3-hydroxy-4-methyl-5-oxooctan-2-yl]-5-methyloxan-2-yl]butano
CAS number	55721-31-8	molecular formula	C42H69NaO11
molecular weight	772.98 g/mol	Exact mass	-
PSA	164.000 Å²	logp	-

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Safety information

pictogram：

GHS06 , GHS08

Signal word：

Danger

Hazard Statement：

H373: 通过长时间或反复暴露对器官造成损害 H300: 吞咽致命

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