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Ilmofosine

Dangerous Goods

CAS number:83519-04-4    molecular formula:C26H56NO5PS

overview

compound introduction

Ilmofosine 是具有抗肿瘤活性的PKC抑制剂,IC 50为560 nM。它在PKC的调控位点起竞争性抑制剂的作用。浓度为1-30μg/ mL的伊莫福辛具有抗多种人类非小细胞肺癌,乳腺癌,结肠直肠癌,卵巢癌和肾细胞癌的功效。 Ilmofosine is a PKC inhibitor with antineoplastic activity with an IC|50|value of 560 nM. It acts as a competitive inhibitor at the regulatory site of PKC. Ilmofosine has efficacy against various human non-small cell lung, breast, colorectal, ovarian, and renal cell cancers at concentrations of 1-30 μg/mL.

Specs

Chinese alias伊莫福新
English aliasD04504 | SCHEMBL48829 | SH-MM-lysolecithin | [2-(hexadecylsulfanylmethyl)-3-methoxypropyl] 2-(trimethylazaniumyl)ethyl phosphate | NCGC00165808-01 | NSC601679 | NSC-601679 | BM 41440 | (+-)-Ilmofosine | Q27263125 | Ilmofosina | ILMOFOSINE | Ilmofosine (US
CAS number83519-04-4molecular formulaC26H56NO5PS
molecular weight525.77 g/molExact mass-
PSA93.100 Ųlogp7.500

numbering system

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physicochemical properties

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Safety information

pictogram:
GHS06
Signal word:
Danger
Hazard Statement:
H301: 吞咽会中毒
Statement of Preventive Measures:
P321: 特殊处理(请参阅此标签上的...)。 P405: 密闭存放 P501: 将内容物/容器处理到。。。 P264: 处理后要彻底洗手。 P270: 使用本产品时,请勿进食、饮水或吸烟。 P330: 漱口 P301+P316: 如果吞咽:立即寻求紧急医疗救助。
WGK Germany:
3
RTECS:
JH4758000
UN Number:
2811
Packing Group:
III

Production methods and uses

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Related

upstream information

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downstream information

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MSDS

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