compound introduction
丙酸氟替卡松-d5是丙酸氟替卡松的标记形式。丙酸氟替卡松是一种高亲和力的选择性糖皮质激素受体（GR）激动剂（K | d | = 0.5 nM）。丙酸氟替卡松有效地刺激糖皮质激素受体介导的基因表达反式激活，并增强人嗜酸性粒细胞的凋亡（EC | 50 | = 3.7 nM）|。丙酸氟替卡松是一种衍生自氟美松的亲脂性抗炎药。 Fluticasone propionate-d5 is the labeled form of fluticasone propionate . Fluticasone propionate is a high affinity, selective glucocorticoid receptor (GR) agonist (K|d|= 0.5 nM). Fluticasone propionate potently stimulates glucocorticoid receptor-mediated transactivation of gene expression and enhances human eosinophil apoptosis (EC|50|= 3.7 nM)|in vitro|. Fluticasone propionate is a lipophilic anti-inflammatory agent derived from flumethasone .
