CAS number：1092788-83-4 molecular formula：C17H17N7
PP121是一种作用于PDGFR， Hck， mTOR， VEGFR2， Src和Abl的多靶点抑制剂，IC50分别为2 nM， 8 nM， 10 nM， 12 nM， 14 nM和18 nM，也抑制DNA-PK，IC50为60 nM。An inhibitor of c-Abl, PI 3-kinase, PDGFR, Hck, FRAP, Flk-1, SRC, and DNA-PK. PP-121 is a multi-targeted inhibitor of PDGFR, Hck, mTOR, VEGFR2, Src and Abl with IC50 of 2 nM, 8 nM, 10 nM, 12 nM, 14 nM and 18 nM, also inhibits DNA-PK with IC50 of 60 nM. An inhibitor of c-Abl, PI 3-kinase, PDGFR, Hck, FRAP, Flk-1, SRC, and DNA-PK.
| Chinese alias | - | ||
| English alias | SW218262-2 | PP121 | PP-121 | 1092788-83-4 | BCP02256 | J-504558 | SB16563 | MLS001032035 | NCGC00346619-01 | AC-28461 | AS-55839 | GTPL8013 | 1H-Pyrazolo[3,4-d]pyrimidin-4-amine, 1-cyclopentyl-3-(1H-pyrrolo[2,3-b]pyridin-5-yl)- | HMS3656D05 | PP 121 | CC | ||
| CAS number | 1092788-83-4 | molecular formula | C17H17N7 |
| molecular weight | 319.36 g/mol | Exact mass | - |
| PSA | 98.300 Ų | logp | 2.100 |
No numbering system information yet
No physical and chemical property information yet
No production method and use information yet
No upstream information yet
No downstream information yet
