必需脂肪酸缺乏症的症状包括免疫系统下降和炎症抑制的一般状态。CP 24,879是花生四烯酸生物合成的抑制剂，通过抑制Δ5/Δ6去饱和酶起作用。以3 mg / kg的CP 24,879注射的小鼠肝花生四烯酸含量降低约50％。用5 µM CP 24,879处理的鼠肥大细胞瘤细胞显示出增加的米德酸含量和白三烯C4合成的几乎完全消融，这与去饱和酶抑制诱导的必需脂肪酸缺乏状态一致。 Essential fatty acid deficiency symptoms include immune system depression and a general state of inflammatory inhibition. CP 24,879 is an inhibitor of arachidonic acid biosynthesis acting via the inhibition of Δ5/Δ6 desaturase. Mice injected with CP 24,879 at 3 mg/kg had a reduction of liver arachidonate content of approximately 50%. Murine mastocytoma cells treated with 5 μM CP 24,879 showed increased mead acid content and nearly complete ablation of leukotriene C4 synthesis, consistent with a desaturase inhibition-induced state of essential fatty acid deficiency.
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CP 24,879 (hydrochloride)
Dangerous GoodsCAS number：10141-51-2 molecular formula：C11H18NOCl
overview
compound introduction
Specs
| Chinese alias | - | ||
| English alias | Benzenamine, 4-(3-methylbutoxy)-, hydrochloride (9CI) | CP-24879 (hydrochloride) | SR-01000946202 | HY-115319 | 4-(isopentyloxy)aniline hydrochloride | 4-(3-methylbutoxy)aniline;hydrochloride | CP 24,879 (hydrochloride) | 4-(3-methylbutoxy)aniline hydroch | ||
| CAS number | 10141-51-2 | molecular formula | C11H18NOCl |
| molecular weight | 215.72 g/mol | Exact mass | ≥98% |
| PSA | 35.300 Ų | logp | - |
numbering system
No numbering system information yet
physicochemical properties
No physical and chemical property information yet
Safety information
pictogram：
GHS07
Signal word：
Warning
Hazard Statement：
H315: 引起皮肤刺激 H319: 引起严重眼睛刺激 H335: 可能引起呼吸道刺激
Statement of Preventive Measures：
P261: 避免吸入灰尘/烟雾/气体/雾/蒸汽/喷雾 P305+P351+P338: 如进入眼睛：用水小心冲洗几分钟。如戴隐形眼镜并可方便地取出，取出隐形眼镜。继续冲洗。 P280: 戴防护手套/穿防护服/戴防护眼罩/戴防护面具。 P302+P352: 如皮肤沾染：用水充分清洗。 P321: 特殊处理（请参阅此标签上的...）。 P405: 密闭存放 P501: 将内容物/容器处理到。。。 P264: 处理后要彻底洗手。 P271: 仅在室外或通风良好的地方使用。 P304+P340: 如误吸入：将人转移
WGK Germany：
3
Personal protective equipment：
dust mask type N95 (US)， Eyeshields， Gloves
Production methods and uses
No production method and use information yet
Related
upstream information
No upstream information yet
downstream information
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MSDS
Found 0 shareMSDS
