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STAT3-IN-1

Dangerous Goods

CAS number:2059952-75-7    molecular formula:C28H29NO6

overview

compound introduction

Information STAT3-IN-1 (compound 7d) is an excellent, selective and orally active inhibitor ofSTAT3with IC50 of 1.82 μM and 2.14 μM in HT29 and MDA-MB 231 cells, respectively. STAT3-IN-1 inducesapoptosisof tumor cells. Targets STAT3 (in HT29 cells); STAT3 (in MDA-MB 231 cells) 1.82 μM; 2.14 μM

Specs

Chinese alias-
English alias2-​Propenamide,N-​[4-​[(1E)​-​2-​(3,​5-​dimethoxyphenyl)​ethenyl]​phenyl]​-​3-​(3,​4,​5-​trimethoxyphenyl)​-​,(2E)​-
CAS number2059952-75-7molecular formulaC28H29NO6
molecular weight475.53 g/molExact mass10mM in DMSO
PSA75.300 Ųlogp4.986

numbering system

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physicochemical properties

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Safety information

pictogram:
GHS07
Signal word:
Warning
Hazard Statement:
H315: 引起皮肤刺激 H319: 引起严重眼睛刺激 H335: 可能引起呼吸道刺激 H302: 吞食有害
Statement of Preventive Measures:
P261: 避免吸入灰尘/烟雾/气体/雾/蒸汽/喷雾 P305+P351+P338: 如进入眼睛:用水小心冲洗几分钟。如戴隐形眼镜并可方便地取出,取出隐形眼镜。继续冲洗。

Production methods and uses

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downstream information

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MSDS

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