Information STAT3-IN-1 (compound 7d) is an excellent, selective and orally active inhibitor ofSTAT3with IC50 of 1.82 μM and 2.14 μM in HT29 and MDA-MB 231 cells, respectively. STAT3-IN-1 inducesapoptosisof tumor cells. Targets STAT3 (in HT29 cells); STAT3 (in MDA-MB 231 cells) 1.82 μM; 2.14 μM
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STAT3-IN-1
Dangerous GoodsCAS number:2059952-75-7 molecular formula:C28H29NO6
overview
compound introduction
Specs
| Chinese alias | - | ||
| English alias | 2-Propenamide,N-[4-[(1E)-2-(3,5-dimethoxyphenyl)ethenyl]phenyl]-3-(3,4,5-trimethoxyphenyl)-,(2E)- | ||
| CAS number | 2059952-75-7 | molecular formula | C28H29NO6 |
| molecular weight | 475.53 g/mol | Exact mass | 10mM in DMSO |
| PSA | 75.300 Ų | logp | 4.986 |
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physicochemical properties
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Safety information
pictogram:
GHS07
Signal word:
Warning
Hazard Statement:
H315: 引起皮肤刺激 H319: 引起严重眼睛刺激 H335: 可能引起呼吸道刺激 H302: 吞食有害
Statement of Preventive Measures:
P261: 避免吸入灰尘/烟雾/气体/雾/蒸汽/喷雾 P305+P351+P338: 如进入眼睛:用水小心冲洗几分钟。如戴隐形眼镜并可方便地取出,取出隐形眼镜。继续冲洗。
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