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KRM-III

Dangerous Goods

CAS number：79220-94-3    molecular formula：C15H12N2S

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overview

compound introduction

KRM-III is a potent and orally active T-cell antigen receptor (TCR) inhibitor. KRM-III inhibits TCR - and phorbol myristate acetate/ionomycin-induced activation of nuclear factor of activated T cells (NFAT) and T-cell proliferation with an IC 50 of ~5 μM. Anti-inflammatory activity. Form:Solid

Specs

Chinese alias核磁共振
English aliasCCG-33458 | Tox21_500376 | HMS2873G11 | SR-01000555374-1 | ChemDiv3_012382 | 1,3-Dihydro-1,4-diphenyl-2H-imidazole-2-thione | AKOS001033074 | DTXSID40353087 | BRD-K66012761-001-01-8 | MS-23566 | 1,4-diphenyl-2,3-dihydro-1H-imidazole-2-thione | SMR00056769
CAS number79220-94-3molecular formulaC15H12N2S
molecular weight252.33 g/molExact mass≥99%
PSA47.400 Ųlogp3.100

numbering system

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physicochemical properties

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Safety information

pictogram：
GHS07
Signal word：
Warning
Hazard Statement：
H302: 吞食有害
Statement of Preventive Measures：
P305+P351+P338: 如进入眼睛：用水小心冲洗几分钟。如戴隐形眼镜并可方便地取出，取出隐形眼镜。继续冲洗。 P280: 戴防护手套/穿防护服/戴防护眼罩/戴防护面具。 P264+P265: 处理后彻底洗手[和…]。不要触摸眼睛。 P337+P317: 如果眼睛刺激持续：寻求医疗帮助。

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