compound introduction
Fmoc-alpha-Me-L-Leu-OH是一种Fmoc保护的亮氨酸衍生物，可能用于蛋白质组学研究和固相肽合成技术。亮氨酸是一种较简单的氨基酸，侧链为异丁基。这种较小的侧链赋予高度的柔韧性，并在并入多肽链时赋予适度的疏水作用。Fmoc基团通常用吡啶等碱去除，这是一种与酸性不稳定Boc基团正交的去保护策略。 Fmoc-alpha-Me-L-Leu-OH is an Fmoc protected leucine derivative that is potentially useful for proteomics studies and solid phase peptide synthesis techniques. Leucine is one of the more simple amino acids - an isobutyl group as the side chain. This smaller side chain confers a high degree of flexibility, and imparts a moderate hydrophobic effect when incorporated into a polypeptide chain. The Fmoc group is typically removed with a base such as pyridine - an orthogonal de-protection strategy to the acid labilie Boc group.
