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Valdecoxib

Dangerous Goods

CAS number:181695-72-7    molecular formula:C16H14N2O3S

overview

compound introduction

Valdecoxib is a prescription NSAID exhibiting anti-inflammatory, analgesic, and antipyretic properties. Valdecoxib inhibits prostaglandin synthesis via Cox-2 inhibition and is used in the treatment of osteoarthritis and theumatoid arthritis. Valdecoxib selectively inhibits Cox-2 (IC50 of 0.005 μM) over Cox-1 (IC50 of 140 μM).A selective inhibitor of Cox-2 Valdecoxib is a prescription NSAID exhibiting anti-inflammatory, analgesic, and antipyretic properties. Valdecoxib inhibits prostaglandin synthesis via Cox-2 inhibition and is used in the treatment of osteoarthritis and theumatoid arthritis. Valdecoxib selectively inhibits Cox-2 (IC50 of 0.005 μM) over Cox-1 (IC50 of 140 μM). A selective inhibitor of Cox-2

Specs

Chinese alias4-(5-甲基-3-苯基-4-异恶唑基)苯磺酰胺 | 伐地昔布
English aliasCondacaps | NCGC00095129-01 | SC 65872 | Tox21_111438 | UNM-0000305814 | Spectrum3_001001 | VALDECOXIB [HSDB] | UNII-2919279Q3W | Valdecoxib | Valdecoxib [USAN] | Valdecoxib [USAN:INN:BAN] | AB00639996-08 | AKOS000280920 | J-011613 | NSC 759846 | Tox21_11
CAS number181695-72-7molecular formulaC16H14N2O3S
molecular weight314.36 g/molExact mass-
PSA94.600 Ųlogp2.6

numbering system

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physicochemical properties

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Safety information

pictogram:
GHS08 , GHS09
Signal word:
Warning
Hazard Statement:
H373: 通过长时间或反复暴露对器官造成损害 H411: 对水生生物有毒并具有长期持续影响 H361: 怀疑破坏生育力或未出生的孩子
Statement of Preventive Measures:
P273: 避免释放到环境中。 P280: 戴防护手套/穿防护服/戴防护眼罩/戴防护面具。 P405: 密闭存放 P501: 将内容物/容器处理到。。。 P260: 不要吸入灰尘/烟雾/气体/雾/蒸汽/喷雾。 P391: 收集溢出物 P203: 使用前,获取、阅读并遵守所有安全说明。 P318: 如果暴露或担心,请就医。 P319: 如果你感到不适,请寻求医疗帮助。
WGK Germany:
3

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MSDS

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