compound introduction
Acetaminophen glucuronide (APAP-glu) is an inactive glucuronide metabolite of Acetaminophen Acetaminophen is a selective cyclooxygenase-2 (COX-2) inhibitor and a potent hepatic N-acetyltransferase 2 (NAT2) inhibitor In Vitro Acetaminophen is metabolized in the liver mainly by glucuronidation and sulfation, thus generating the nontoxic metabolites, Acetaminophen glucuronide (APAP-glu). Acetaminophen glucuronide is a substrate for both canalicular Mrp2 and basolateral Mrp3 in rodents. MCE has not independently confirmed the accuracy of these methods. They are for reference only. Form:Solid IC50& Target:Human Endogenous Metabolite
