Vicriviroc maleate

Dangerous Goods

CAS number：599179-03-0 molecular formula：C32H42F3N5O6

overview

Specs

numbering system

physicochemical properties

Safety information

Production methods and uses

MSDS

overview

compound introduction

Information Vicriviroc (SCH-417690, SCH-D) maleate is a potent, selective, oral bioavailable and CNS penetrated antagonist of CCR5 with Ki of 2.5 nM. Vicriviroc also inhibits HIV-1 in PBMC cells, with IC90 of 3.3 nM (JrFL), 2.8 nM (ADA-M), 1.8 nM (301657), 4.9 nM (JV1083) and 10 nM (RU 570), respectively.

Specs

Chinese alias	马来酸维可韦洛克
English alias	J-690330 \| MS-30958 \| SCH-417690 (maleate) \| VICRIVIROC MALEATE [MI] \| (Z)-but-2-enedioic acid;(4,6-dimethylpyrimidin-5-yl)-[4-[(3S)-4-[(1R)-2-methoxy-1-[4-(trifluoromethyl)phenyl]ethyl]-3-methylpiperazin-1-yl]-4-methylpiperidin-1-yl]methanone \| Vicriviro
CAS number	599179-03-0	molecular formula	C32H42F3N5O6
molecular weight	649.7 g/mol	Exact mass	-
PSA	136.000 Å²	logp	-

numbering system

No numbering system information yet

physicochemical properties

No physical and chemical property information yet

Safety information

pictogram：

GHS08 , GHS07

Signal word：

Warning

Hazard Statement：

H319: 引起严重眼睛刺激 H373: 通过长时间或反复暴露对器官造成损害 H302: 吞食有害

Statement of Preventive Measures：

P305+P351+P338: 如进入眼睛：用水小心冲洗几分钟。如戴隐形眼镜并可方便地取出，取出隐形眼镜。继续冲洗。 P280: 戴防护手套/穿防护服/戴防护眼罩/戴防护面具。 P501: 将内容物/容器处理到。。。 P264: 处理后要彻底洗手。 P260: 不要吸入灰尘/烟雾/气体/雾/蒸汽/喷雾。 P270: 使用本产品时，请勿进食、饮水或吸烟。 P330: 漱口 P264+P265: 处理后彻底洗手[和…]。不要触摸眼睛。 P301+P317: 如果被吞咽：请寻求医疗帮助。 P337+P317: