Protein Function:: CD30, also known as TNFRSF8, is a cell membrane protein of the tumor necrosis factor receptor (TNFR) superfamily. CD30 protein is expressed by activated, but not resting, T and B cells. CD30 can regulate proliferation of lymphocytes and may also play an important role in human immunodeficiency virus replication. As a regulator of apoptosis, CD30 protein induces cell death or proliferation, depending on the cell type, and has been shown to limit the proliferative potential of autoreactive CD8 effector T cells and protect the body against autoimmunity. CD30 protein expression is upregulated in various hematological malignancies, including Reed-Sternberg cells in Hodgkin's disease (HD), anaplastic large cell lymphoma (ALCL) and subsets of Non-Hodgkin's lymphomas (NHLs), and CD30 is also linked to leukocytes in patients with chronic inflammatory diseases, including lupus erythematosus, asthma, rheumatoid arthritis and atopic dermatitis (AD).
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Recombinant Human CD30/TNFRSF8 Protein
CAS number:unknown molecular formula:
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| Chinese alias | 重组人CD30/TNFRSF8蛋白 | 重组人 CD30/TNFRSF8 蛋白 | ||
| English alias | CD30 | CD30KI-1 | CD30L receptor | cytokine receptor CD30 | D1S166EKi-1 | Ki-1 antigen | Lymphocyte activation antigen CD30 | TNFRSF8 | tumor necrosis factor receptor superfamily member 8 | tumor necrosis factor receptor superfamily, member 8 | CD30 antig | ||
| CAS number | unknown | molecular formula | |
| molecular weight | - | Exact mass | 无动物源 |
| PSA | - | logp | - |
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