compound introduction
Purity > 95 % by SDS-PAGE and HPLC analyses. Endotoxin level is less than 1 EU/µg. Function 4-1BBL is a member of the tumor necrosis factor (TNF) receptor family. Cytokine that binds to TNFRSF9. This receptor contributes to the clonal expansion, survival, and development of T cells. May have a role in activation-induced cell death (AICD). May play a role in cognate interactions between T-cells and B-cells/macrophages.In addition, 4-1BBL expression is found on dendritic cells, follicular dendritic cells, natural killer cells, granulocytes and cells of blood vessel walls at sites of inflammation.
