CAS number：2254609-27-1 molecular formula：C59H67F2N7O11S
SJFα is a 13-atom linker PROTAC based on von Hippel-Lindau ligand. SJFα degrades p38α with a DC 50 of 7.16 nM, but is far less effective at degrading p38δ (DC 50 =299 nM) and does not degrade the other p38 isoforms (β and γ) at concentrations up to 2.5 µM Form:Solid IC50& Target:p38α 7.16 nM (DC 50 ) p38δ 299 nM (DC 50 ) VHL
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| English alias | - | ||
| CAS number | 2254609-27-1 | molecular formula | C59H67F2N7O11S |
| molecular weight | 1120.27 g/mol | Exact mass | ≥99% |
| PSA | - | logp | - |
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