CAS number：2767440-24-2 molecular formula：C41H52N6O6S2
PROTAC AR-V7 degrader-1 (Compound 6) is a potent, orally bioavailable and selective AR-V7 degrader with the DC 50 of 0.32 µM by recruiting VHL E3 ligase to Androgen receptor (AR) DNA binding domain (DBD) binder. PROTAC AR-V7 degrader-1 exhibits activity against 22Rv1 cell-line expressing AR-V7 with the EC 50 of 0.88 µM Form:Solid IC50& Target:VHL
| Chinese alias | PROTAC AR-V7 降解剂-1 | ||
| English alias | - | ||
| CAS number | 2767440-24-2 | molecular formula | C41H52N6O6S2 |
| molecular weight | 789.02 g/mol | Exact mass | ≥99% |
| PSA | - | logp | - |
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