compound introduction
PROTAC ER Degrader-4 is a von Hippel-Lindau -based PROATC estrogen receptor ( ER ) degrader, binding to ER with an IC50 of 0.8 nM. PROTAC ER Degrader-4 induces ER degradation in MCF-7 cells with an IC 50 of 0.3 nM In Vitro PROTAC ER Degrader-4 shows equal to 100% ER degradation at 0.3 μM in the MCF-7 ER degradation cellular assay. MCE has not independently confirmed the accuracy of these methods. They are for reference only. Form:Solid IC50& Target:VHL ER
