SHP2 protein degrader-2 (SHP2-D26) is a SHP2 protein PROTAC degrader. SHP2 protein degrader-2 reduces expression level of SHP2 in various cancer cells. In Vitro SHP2 protein degrader-2 (SHP2-D26) achieves excellent degradation of SHP2 with the DC 50 (the concentration where 50% of the protein has been degraded) values of 2.6 nM and 6.0 nM for MV4;11 and KYSE520 cells, respectively. MCE has not independently confirmed the accuracy of these methods. They are for reference only. Form:Solid
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SHP2 protein degrader-2
CAS number:2740582-16-3 molecular formula:C56H79ClN12O6S2
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| Chinese alias | SHP2蛋白降解剂-2 | ||
| English alias | - | ||
| CAS number | 2740582-16-3 | molecular formula | C56H79ClN12O6S2 |
| molecular weight | 1115.89 g/mol | Exact mass | ≥98% |
| PSA | - | logp | - |
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