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Thalidomide-PEG2-NH2 hydrochloride

CAS number:unknown    molecular formula:C17H20ClN3O6

overview

compound introduction

Thalidomide-PEG2-NH2 hydrochloride is a synthesized E3 ligase ligand-linker conjugate ( E3 Ligase Ligand-Linker Conjugates ) that incorporates the Thalidomide ( Thalidomide (HY-14658) ) based cereblon ligand and a linker used in PROTAC technology. Appearance:Solid IC50& Target:Cereblon In Vitro:PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins. MCE Biological Activity:Thalidomide-PEG2-NH2 hydrochloride is a synthesized E3 ligase ligand-linker conjugate ( E3 Ligase Ligand-Linker Conjugates ) that incorporates the Thalidomide ( Thalidomide (HY-14658) ) based cereblon ligand and a linker used in PROTAC technology.

Specs

Chinese alias沙利度胺-PEG2-NH2 盐酸盐
English alias-
CAS numberunknownmolecular formulaC17H20ClN3O6
molecular weight397.81 g/molExact mass≥95%
PSA-logp-

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